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Interactions between cationic peptides and negatively charged oligonucleotides can enhance toxicity, affect pharmacokinetic and pharmacological properties, and limit the efficacy of these therapies

Groups of male mice (1213 weeks, 22.528.5 g, 56 mice/23 cages/group) were fasted for 4 h prior to IP injection of unfused WT albumin (0.9 mg/kg) or GLP-1 albumin fusions (1 mg/kg)

To view or add a comment, sign in The global is predicted to reach . by 2030 with a .% by 2030